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EDS is a genetic connective tissue disorder which can be classified 13 different ways. Some key features which distinguish this disease are joint hypermobility, skin fragility, joint pain without arthritis, and rupture of blood vessels and internal organs. This pathology can present itself at any age, and no particular type is more common than another. Ethnicity, race, and gender do not seem to determine prevalence of this disease. 1 in every 20,000 people are diagnosed with classical EDS (Ghali et al., 2019). The process of diagnosing a patient includes examination of medical history, skin and musculoskeletal system, and other factors through primary and secondary care. Pharmacological strategies are targeted at symptom management. For example, benzodiazepines such as Valium or Xanax can be used to treat restless leg syndrome. Benzodiazepines act as a tranquilizer to reduce the muscle spasms in restless leg syndrome (Castori et al., 2012). The Beighton scoring system is primarily used to diagnose joint hypermobility, which is a key indicator of the presence of EDS. Other criteria for diagnosing EDS include: unusual skin characteristics, positive family history for EDS, musculoskeletal pain, recurrent joint dislocations/instability, and skin fragility(Ghali et al.,2019).

Publication Date

Spring 2021


Boiling Springs, NC


Medicine and Health Sciences | Movement and Mind-Body Therapies | Rehabilitation and Therapy | Sports Sciences

Exercise Prescription for Patients with Ehlers-Danlos Syndrome