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Abstract

Background: This systematic review of reviews and meta-analyses provides education leaders with ten years of evidence-based strategies for effective adolescent substance use prevention. Methods: Following the PRISMA 2020 protocol for systematic reviews, we searched the PubMed and PsychINFO databases on October 19, 2023, and identified 96 systematic literature reviews and meta-analyses involving adolescent drug use prevention from 2103-2023. Twenty-four papers met the criteria for final inclusion. Results: Educational leaders should know three areas to deliver effective evidence-based adolescent substance prevention: 1) foundational understanding of risk and protective factors, 2) components of effective prevention programs, and 3) drug-specific prevention outcomes. Discussion: Today’s illicit drug supply is deadlier than ever, so education leaders must expose students to universal school

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